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Updated: Jan 13, 2026

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data
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Published on: June 24, 2021

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Stage-Specific Alternative Polyadenylation During Human Neural Differentiation Revealed by Integrated Long- and

Zheqi Lou1, Xianyan Zeng1,2, Tinghui Jiang1

  • 1College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.

Biology
|January 10, 2026
PubMed
Summary

This study reveals novel insights into alternative polyadenylation (APA) during human embryonic stem cell (hESC) neural differentiation. The research identifies thousands of new transcripts and poly(A) sites, enhancing our understanding of cell-fate regulation.

Keywords:
Oxford Nanopore Technologiesalternative polyadenylationexon alternative polyadenylationhuman embryonic stem cellsintronic alternative polyadenylationneural differentiationshort-read sequencing

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