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Prospective, Multicentre Feasibility Study of Remote Colon Capsule Endoscopy Using the OMOM CC100 System.

Alexandra Agache1,2,3, Ervin Toth4,5, Niels Qvist2

  • 1Department of Clinical Research, University of Southern Denmark (SDU), 5000 Odense C, Denmark.

Diagnostics (Basel, Switzerland)
|January 10, 2026
PubMed
Summary
This summary is machine-generated.

Colon capsule endoscopy (CCE) using the OMOM CC100 system is safe and feasible, demonstrating good diagnostic yield for various gastrointestinal conditions. Remote administration enhances patient satisfaction and accessibility, supporting decentralized care models.

Keywords:
administrationcapsule endoscopycolonoscopydiagnostic yieldpatient satisfaction

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Area of Science:

  • Gastroenterology
  • Medical Devices
  • Endoscopy

Background:

  • Colon capsule endoscopy (CCE) offers a non-invasive alternative to conventional colonoscopy.
  • Decentralized care models are emerging for improved accessibility in gastrointestinal diagnostics.

Purpose of the Study:

  • To evaluate the feasibility, safety, diagnostic yield, and patient satisfaction of the OMOM CC100 CCE system.
  • To assess the efficacy of fully and partially remote administration for advancing decentralized CCE models.

Main Methods:

  • A prospective, international multicenter feasibility study involving 119 patients (aged 18-75).
  • Utilized the OMOM CC100 capsule with standardized bowel preparation.
  • Compared fully remote (IntelliGI™ platform) and partially remote administration across four European centers.

Main Results:

  • Overall completion rate was 79%, with adequate bowel cleanliness in 71% of patients.
  • Diagnostic yield included polyps (25), angioectasia (20), and mucosal inflammation (17); 42% of examinations were normal.
  • Fully remote administration achieved 80% completion and 89.7% satisfaction; overall patient satisfaction was 81%.

Conclusions:

  • The OMOM CC100 CCE system is feasible, safe, and offers a diagnostic yield comparable to existing systems.
  • IntelliGI™-enabled remote administration facilitates decentralized CCE, improving accessibility and patient preference for home-based procedures.