Related Experiment Video
Updated: Jan 13, 2026

09:44
Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Published on: March 5, 2022
3.3K
AMH in PCOS and Beyond-Rare Case Series.
Ralitsa Robeva1,2, Tzvetozar Mehandjiev3, Roumen Dimitrov4
1Department of Endocrinology, Faculty of Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Diagnostics (Basel, Switzerland)
|January 10, 2026
Summary
Anti-Müllerian hormone (AMH) is crucial for diagnosing ovarian disorders. Rare cases highlight AMH
Area of Science:
- Reproductive Endocrinology
- Gynecology
- Oncology
Background:
- Anti-Müllerian hormone (AMH) is a key biomarker for ovarian function and diagnosis of various gynecological conditions.
- Elevated AMH levels are associated with Polycystic Ovary Syndrome (PCOS), but clinical utility is hindered by analytical variability and inconsistent thresholds.
- Differential diagnosis of elevated AMH is complex, involving conditions beyond PCOS such as pituitary dysfunction, ovarian enlargement, and granulosa cell tumors (GCTs).
Related Concept Videos
Hormonal Control of the Ovarian Cycle
6.4K
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
6.4K
Disorders of the Female Reproductive System
3.8K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.8K
Hypothalamic-Pituitary Axis
65.4K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.4K
Oogenesis
69.0K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
69.0K

