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Related Concept Videos

Factors Affecting Solubility04:01

Factors Affecting Solubility

Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations01:15

Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations

Gentamicin, an aminoglycoside antibiotic, is commonly administered via intermittent intravenous infusion to treat severe infections. An intermittent one-hour infusion of gentamicin, administered at eight-hour intervals, allows for precise control of plasma drug concentrations, minimizing toxicity while ensuring therapeutic efficacy. Pharmacokinetic principles govern the dynamics of plasma concentrations and can be mathematically described using specific equations.The plasma drug concentration...
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses01:25

Determination of Multiple Dosing Parameters: Loading and Maintenance Doses

A loading dose is an essential pharmacological strategy to rapidly achieve the target plasma drug concentration necessary for an immediate therapeutic effect. This approach is especially critical for drugs characterized by slow absorption or extended half-lives, where delaying therapeutic plasma levels could compromise treatment outcomes. By administering a loading dose, clinicians ensure a prompt onset of drug action, even for agents with complex pharmacokinetic profiles.Achieving steady-state...

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Fractionated Anionic PAM Dosing Under High Salinity: Controlling Floc Growth and Stability.

Jahir Ramos1, Eder Piceros2, Tiare D Medina3

  • 1Departamento de Ingeniería Química y Procesos de Minerales, Facultad de Ingeniería, Universidad de Antofagasta, Antofagasta 1240000, Chile.

Polymers
|January 10, 2026
PubMed
Summary

Fractional dosing of anionic polyacrylamide (PAM) improves mineral processing in seawater. A three-pulse dosing strategy significantly enhances floc settling rates and structural integrity, outperforming single-dose methods.

Keywords:
FBRMadsorption–bridgingaggregate densityanionic polyacrylamidefractal dimensionfractionated dosingseawater flocculationsize distributions

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Area of Science:

  • Mineral Processing
  • Colloid and Surface Chemistry
  • Water Treatment

Background:

  • Seawater use in mineral processing complicates solid-liquid separation due to polymer issues.
  • Challenges include polymer chain contraction, coagulation, and brittle aggregates.

Purpose of the Study:

  • To evaluate fractional dosing of anionic polyacrylamide (PAM) for floc formation and sedimentation in seawater.
  • To compare single-pulse versus multi-pulse dosing strategies for quartz-kaolinite suspensions.

Main Methods:

  • Fractional dosing of PAM (1-4 pulses) in quartz-kaolinite seawater suspensions.
  • Analysis using sedimentation assays, FBRM, size distributions, fractal dimensions, and zeta potential.

Main Results:

  • All fractional dosing schemes outperformed single-pulse dosing.
  • A three-pulse strategy (0-30-60 s) yielded the highest settling rates and fines reduction.
  • Multi-pulse dosing resulted in more compact, robust flocs with stepped growth and stable maturation.

Conclusions:

  • Fractional PAM dosing mitigates issues associated with seawater processing.
  • Progressive polymer availability enhances bridging efficiency and reduces brittle aggregate formation.
  • The three-pulse method offers superior performance for solid-liquid separation in high-salinity conditions.