Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

14.1K
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This is referred to as “The Central Dogma of Molecular Biology” - a term coined by Francis Crick.  Central dogma is a firm principle in biology that defines the flow of genetic information within any life form. The two fundamental steps in central dogma are - transcription and translation.
Transcription is the synthesis of RNA...
14.1K
Proteins: From Genes to Degradation02:11

Proteins: From Genes to Degradation

4.2K
4.2K
Protein Transport to the Inner Chloroplast Membrane01:18

Protein Transport to the Inner Chloroplast Membrane

2.4K
Proteins targeted to the inner chloroplast membrane, or plastid proteins, are transported by two general pathways: the stop-transfer and the re-insertion or post-import pathways. Most plastid proteins carry N-terminal transit sequences and internal import sequences targeting it to the specific chloroplast subcompartment. Proteins targeted by the stop-transfer pathway have internal hydrophobic sequences that inhibit their translocation into the stroma. As a result, these precursors are arrested...
2.4K
Cell Signaling in Plants01:25

Cell Signaling in Plants

6.1K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
6.1K
Regulated Protein Degradation02:58

Regulated Protein Degradation

3.1K
3.1K
Regulated Protein Degradation02:58

Regulated Protein Degradation

8.7K
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells.
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detecting cryptic ghost lineage introgression in four-taxon genomic datasets.

Applications in plant sciences·2026
Same author

The Effects of Rapid Mitochondrial Gene Loss on Organellar Proteomes.

Genome biology and evolution·2026
Same author

Silene, a versatile model system: from sex and genome evolution to ecology and speciation.

The New phytologist·2026
Same author

Sensitivity of genome-wide tests for mitonuclear genetic incompatibilities.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same author

Reshaping organellar translation and tRNA metabolism: the consequences of photosynthesis loss and massive horizontal gene transfer.

Molecular biology and evolution·2026
Same author

Plant MutS2 proteins function in plastid ribosome quality control.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Jan 13, 2026

A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry
08:04

A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry

Published on: March 13, 2014

12.6K

Correlated Evolutionary Rates Reveal Novel Components and Cross-Compartment Connectivity in Plant Proteostasis

Tony C Gatts1, Elizabeth A Rehmann2, Linnea E Lane3

  • 1Department of Biology, Colorado State University, Fort Collins, CO, USA.

Genome Biology and Evolution
|January 10, 2026
PubMed
Summary

This study reveals a plant protein network linked by evolutionary rate covariation (ERC). It identifies a functional module involved in plastid proteostasis, including unexpected proteins that may mediate organellar communication.

Keywords:
evolutionary rate covariationinteractomephylogenomicsplastid proteostasis

More Related Videos

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
12:38

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism

Published on: December 18, 2013

6.5K
Assaying Proteasomal Degradation in a Cell-free System in Plants
07:43

Assaying Proteasomal Degradation in a Cell-free System in Plants

Published on: March 26, 2014

15.0K

Related Experiment Videos

Last Updated: Jan 13, 2026

A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry
08:04

A New Approach for the Comparative Analysis of Multiprotein Complexes Based on 15N Metabolic Labeling and Quantitative Mass Spectrometry

Published on: March 13, 2014

12.6K
Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
12:38

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism

Published on: December 18, 2013

6.5K
Assaying Proteasomal Degradation in a Cell-free System in Plants
07:43

Assaying Proteasomal Degradation in a Cell-free System in Plants

Published on: March 26, 2014

15.0K

Area of Science:

  • Plant Biology
  • Molecular Biology
  • Proteostasis Network Analysis

Background:

  • Plant cells utilize complex protein networks for various functions.
  • Evolutionary Rate Covariation (ERC) signatures indicate functional protein interactions.
  • Understanding these networks is crucial for plant cell biology.

Purpose of the Study:

  • To predict a plant protein-protein interactome network using genome-scale ERC analyses.
  • To identify functional modules within the plant proteostasis system.
  • To discover novel proteins involved in plastid proteostasis.

Main Methods:

  • Genome-scale Evolutionary Rate Covariation (ERC) analyses were performed.
  • Protein interaction networks were predicted based on ERC signatures.
  • Functional modules related to plastid proteostasis were identified.

Main Results:

  • A clustered set of proteins exhibiting strong ERC signatures with plastid proteostasis components was identified.
  • This functional module includes known and novel proteins involved in plastid functions.
  • Surprisingly, proteins localized outside the plastid, including mitochondrial and nuclear proteins, were part of this module.

Conclusions:

  • Plant proteostasis systems are highly interconnected.
  • Novel proteins, including those outside the plastid, may play roles in plastid proteostasis and organellar crosstalk.
  • The study identifies promising candidates for further investigation into plant proteostasis mechanisms.