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Related Concept Videos

iPS Cell Differentiation01:22

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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Related Experiment Video

Updated: Jan 13, 2026

Generation of Human Microglia to Combine Them with Retinal Organoids for Improved Disease Modeling
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Exploring retinal microglia: development, degeneration, and iPSC-derived model systems

Mei-Ling Gao1,2, Ya-Yi Ju3,4, Jun Zhang5,6

  • 1State Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China. gaoml@wmu.edu.cn.

Brain Structure & Function
|January 10, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
Retinal microglia; iPSC-derived microglia; Chimeric models; Retinalorganoids; Neuroinflammation.

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