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Updated: May 8, 2026

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In silico identification of deleterious NT5C2 and PRPS1 mutations driving thiopurine resistance in relapsed acute

Ramita Sharma1, Jeeshitha Kudithipudi2, Himanshu Singh3

  • 1Research and Development, Indo-American Cancer Research Foundation, Basavatarakam Indo-American Cancer Hospital and Research Institute, Banjara Hills, Hyderabad, Telangana 500034, India; School of Bioengineering and Biosciences, Lovely Professional University, Punjab, India.

Cancer Genetics
|January 10, 2026
PubMed

Keywords:
In silico analysisMD simulationMolecular dockingRelapsed acute lymphoblastic leukemiaThiopurine resistancensSNPs

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