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Updated: Jan 13, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
Published on: October 8, 2017
Semantic design: Programming functional genes from genomic context
1Biological Science Research Center, Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, Chongqing Technology Innovation Center of Breeding, Academy for Advanced Interdisciplinary Studies, Southwest University, Chongqing 400715, China.
Abstract:
Generative genomic models hold immense potential for creating intricate biological systems, yet designing precise functional sequences remains challenging. Merchant et al. in Nature present semantic design, which employs the Evo genomic language model to generate novel functional genes based solely on genomic context. Moreover, SynGenome database houses over 120 billion sequences generated through semantic design, spanning a diverse range of functions.
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