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Letter to the editor: "Recovery of motor functions and cognitive functions in patients with intensive care
1Department of Clinical Medicine, Graduate School of Qinghai University, Xining, Qinghai 810000, China.
Abstract:
We congratulate Aoyama et al. for demonstrating that cognitive status at ICU discharge is linked to 4-week motor recovery in ICU-AW survivors (J Crit Care 2026; 91:155273). We caution, however, against causal over-interpretation of this retrospective cohort, urge adoption of target-trial emulation (inverse-probability weighting or instrumental variables) and a prospective, adequately powered (≈ 120 patients) multicentre RCT. Routine post-ICU cognitive screening (MoCA) and delirium monitoring (CAM-ICU) could enable early triage to multidisciplinary rehabilitation and should be validated in nationwide data.
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