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Related Concept Videos

Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Hormonal Regulation of the Menstrual Cycle01:22

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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Hormonal Control of the Ovarian Cycle01:30

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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
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Introspection01:29

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Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
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Psychodynamic Therapy01:29

Psychodynamic Therapy

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Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
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Hormonal Regulation01:40

Hormonal Regulation

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Related Experiment Video

Updated: Jan 13, 2026

Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model
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Author Spotlight: Investigating the Relationship Between FSH and Pathophysiological Changes in Perimenopausal Women - Insights from a Mouse Model

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Integrative approaches to perimenopause.

Anne Kennard1, Kelley T Saunders2

  • 1Marian Regional Medical Center, Santa Maria, CA, USA.

The American Journal of Medicine
|January 11, 2026
PubMed
Summary
This summary is machine-generated.

Managing perimenopause involves integrative strategies for symptom relief and long-term health. Lifestyle, nutrition, and therapies can enhance well-being during this transition.

Keywords:
Integrative Medicinelifestyle medicinemenopausenutritionperimenopausesupplements

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Area of Science:

  • Integrative medicine
  • Women's health
  • Reproductive endocrinology

Background:

  • Perimenopause is characterized by hormonal fluctuations leading to vasomotor symptoms, mood changes, sleep disturbances, and metabolic shifts.
  • Effective management strategies are crucial for improving quality of life and promoting long-term health during this transitional phase.

Purpose of the Study:

  • To review integrative approaches for managing perimenopausal symptoms.
  • To explore strategies promoting long-term health and well-being in women transitioning through perimenopause.

Main Methods:

  • Literature review of nutritional strategies, movement and mind-body practices, and selected supplements.
  • Evaluation of evidence for conventional therapies like hormone therapy.
  • Focus on individualized care integrating various therapeutic modalities.

Main Results:

  • Nutritional strategies (plant-forward diets, phytoestrogens) may alleviate vasomotor symptoms and support cardiovascular/bone health.
  • Movement and mind-body practices (yoga, resistance training) enhance physical and psychological well-being.
  • Supplements show variable promise for sleep, mood, and sexual function; hormone therapy is effective for vasomotor/genitourinary symptoms.

Conclusions:

  • Individualized care integrating lifestyle, nutritional, botanical, and conventional therapies enhances quality of life and supports healthy aging.
  • Shared decision-making empowers patients by tailoring interventions to preferences and risks.
  • Integrative approaches are key to supporting women through the menopause transition and beyond.