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Biomechanical Analysis of Customized 3D-Printed Orthodontic Archwires Using Finite Element Modeling and Clinical
Mohammad K Alam1,2,3, Mohammad Y Hajeer4, Nuha A Alsalamah1
1Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Journal of Pharmacy & Bioallied Sciences
|January 12, 2026
Summary
Customized 3D-printed orthodontic archwires offer superior biomechanical performance and patient comfort compared to traditional options. This innovative approach enhances treatment efficiency and patient experience in orthodontics.
Area of Science:
- Biomaterials Science
- Orthodontics
- Additive Manufacturing
Background:
- Orthodontic treatment relies on archwire biomechanics, but conventional materials lack personalization.
- Patient-specific anatomy challenges standardized archwire designs.
- Additive manufacturing enables fabrication of customized 3D-printed orthodontic archwires.
Purpose of the Study:
- To evaluate the biomechanical performance and clinical efficacy of customized 3D-printed orthodontic archwires.
- To compare 3D-printed archwires with standard and preformed designs using finite element method (FEM) simulations and clinical trials.
- To assess alignment efficiency, patient discomfort, and anchorage loss associated with customized archwires.
Main Methods:
- A two-phase study combining in silico FEM simulation and clinical validation.
- FEM analysis of standard, preformed, and customized 3D-printed archwires under uniform loading.
- Clinical trial with 30 Class I malocclusion patients randomized to standard or 3D-printed archwires over eight weeks.
Main Results:
- FEM simulations revealed significantly lower von Mises stress in customized archwires (68.4 MPa) versus standard (96.7 MPa) and preformed (84.3 MPa) wires (P < 0.01).
- Customized archwires demonstrated improved force distribution and reduced peak displacement.
- Clinically, the 3D-printed group showed 38.2% greater alignment (P = 0.004), reduced discomfort (VAS 3.1 vs. 5.4; P < 0.001), and comparable anchorage control.
Conclusions:
- Customized 3D-printed orthodontic archwires exhibit superior biomechanical efficiency and enhanced patient comfort.
- These patient-specific archwires represent a promising advancement in orthodontic treatment.
- FEM-guided design principles are crucial for optimizing next-generation orthodontic tools like 3D-printed archwires.

