Related Experiment Video
Updated: Jan 13, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Ablation for Atrial Fibrillation: Can We Individualise Therapy or Should One Size Fit All?
Nick B Spath1, Ruairidh Martin2, Moloy Das2
1Department of Cardiology, Edinburgh Royal Infirmary, EH16 4SA Edinburgh, UK.
None:
Modern medicine increasingly offers the potential to individualise patient care and tailor therapies to meet specific patient needs. Catheter ablation in atrial fibrillation has undergone radical evolution since the advent of early ablative therapies; however, more comprehensive or extensive strategies are now possible. Moreover, novel energy sources, catheters, and mapping platforms are being developed and implemented, raising the potential to deliver ablation strategies more effectively, durably, quickly, and potentially more extensively. This poses the challenge of whether to prioritise anatomical landmark-based ablation or pursue individual mechanisms of arrhythmia on a personalised basis. Thus, this review aims to summarise the current state-of-the-art developments in catheter ablation for atrial fibrillation, recent advances, and developments in both the ablation and understanding of arrhythmia pathophysiology.
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Dosage Regimen: Individualization
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Venous Thrombosis III: Interprofessional Care

