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Published on: July 25, 2025
Molecular communication system using Zn2+ selective supramolecular nanochannel to induce photoregulated catalysis
Soumya Srimayee1, Biswa Mohan Prusty1, Mrinal Kanti Kar1
1Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, India. dmanna@iitg.ac.in.
Abstract:
We developed synthetic ionophores that self-assemble into supramolecular nanochannels for the transport of Zn2+ across lipid bilayers. The translocated Zn2+ forms a photoactive PPIX-Zn2+ complex that generates 1O2 to oxidize tryptophan, establishing a Zn2+-mediated cascade reaction network within confined spaces, which is crucial for developing photoregulated molecular communication systems.
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