[Frequency and spatial characteristics of EEG in patients with coronary artery disease with preserved cognitive status and cognitive disorders]

The objective of this study was to investigate the effect of coronary artery disease (CAD) on the frequency and spatial characteristics of the electroencephalogram (EEG) in patients with preserved cognitive status and those with cognitive impairment.

The study included 132 patients with stable coronary artery disease and 63 subjects in a group of apparently healthy elderly people. All patients underwent neuropsychological screening, and based on the results, they were divided into two groups: those without cognitive impairment (CI) who scored 27-30 points on the Montreal Cognitive Assessment Scale (MoCA) (n=37) and those with CI who scored 20-26 points on the MoCA scale (n=95). Patients and healthy subjects also underwent a high-resolution EEG.

It was found that the differentiation between groups of CAD patients with and without CI and healthy elderly individuals occurs at the frequencies of theta1, theta2, and alpha2 rhythms, with local differences in the power of theta1 biopotentials and global differences in the theta2 and alpha2 ranges.

The presented results demonstrate that patients with CAD and cognitive impairment exhibit specific features in the frequency and spatial characteristics of brain electrical activity compared to those of healthy elderly individuals.