Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: Association of sarcopenia with survival and treatment response in brain metastasis of non-small cell lung cancer.

Scientific reports·2026

Same author

Postoperative fractionated stereotactic radiotherapy for completely resected brain metastases with 25 Gy in five fractions: A single-center retrospective study.

Clinical and translational radiation oncology·2026

Same author

Repeat radiofrequency thermocoagulation for multiple sclerosis-associated versus idiopathic trigeminal neuralgia: a comparison of long-term pain control.

Journal of neurosurgery·2026

Same author

Predictors of deep brain stimulation response in patients with obsessive compulsive disorder: a systematic review and meta-analysis.

Scientific reports·2026

Same author

The role of bone flap explantation in the recurrence of surgical site infection after elective craniotomy: A multicenter propensity-matched cohort study.

Neurosurgical review·2026

Same author

Postoperative brain abscesses and infections after neurosurgery: Clinical characteristics, risk profiles, microbiological findings, and longitudinal DWI and ADC MRI analysis.

Brain & spine·2026

Same journal

Definitive IMRT alone with reduced prophylactic nodal irradiation for Early-Stage Oropharyngeal Cancer: JCOG1208.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same journal

Associations between body composition and radiotherapy-related side-effects and health-related quality of life in patients with prostate or lung cancer: sub-analysis of the REQUITE trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same journal

ESTRO recommendations for the use, planning and delivery of reirradiation in locally recurrent rectal cancer - Endorsed by ASTRO.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same journal

Early ADC changes in risk-model-defined brain regions precede contrast-enhancing lesions after proton therapy for low-grade glioma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same journal

Any impact of pre-operative radiotherapy on renal function in retroperitoneal soft tissue sarcomas? A secondary ancillary analysis of the EORTC 62092 STRASS 1 trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

Same journal

Tumor volume reduction during adaptive radiotherapy is a strong prognostic factor for oropharyngeal cancer: A retrospective multicenter study?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 2, 2026

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Published on: October 18, 2011

AI-based assessment of brain volume decrease after treatment with stereotactic radiosurgery versus whole brain

Frederic Thiele¹, Maria Kawula², Sophie Katzendobler¹

¹Department of Neurosurgery, LMU University Hospital, Munich, Germany.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology

|January 12, 2026

Summary

This summary is machine-generated.

Stereotactic Radiosurgery (SRS) and Whole-Brain Radiotherapy (WBRT) both reduce brain volume in patients with brain metastases. SRS appears to cause less pronounced brain volume decrease than WBRT.

Keywords:

Artificial Intelligence Brain Atrophy Brain Metastases Oncology Radiotherapy

More Related Videos

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Published on: March 6, 2012

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Related Experiment Videos

Last Updated: May 2, 2026

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

Published on: October 18, 2011

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model

Published on: March 6, 2012

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

Published on: December 28, 2017

Area of Science:

Neuro-oncology
Radiotherapy research
Brain imaging analysis

Background:

Radiotherapy is crucial for brain metastases but its long-term effects on brain parenchyma are unclear.
Understanding differential volumetric changes between Stereotactic Radiosurgery (SRS) and Whole-Brain Radiotherapy (WBRT) is essential.

Purpose of the Study:

To compare volumetric brain alterations following SRS versus WBRT in patients with brain metastases.
To quantify differences in brain volume decrease between SRS and WBRT.

Main Methods:

Volumetric analysis of cerebrospinal fluid (CSF) space was used to measure brain volume decrease.
Patients with 4-10 brain metastases treated with SRS (n=29) or WBRT (n=30) were included.
Artificial intelligence (UNesT) was employed for image segmentation after registration to MNI305 space.

Main Results:

Both SRS and WBRT led to significant increases in ventricular system volume.
WBRT was associated with more pronounced ventricular enlargement compared to SRS, both in absolute and relative terms.
The study found statistically significant differences in ventricular volume increase between WBRT and SRS groups (p < 0.0001).

Conclusions:

Radiotherapy, including SRS and WBRT, is associated with a decrease in brain volume.
The brain volume decrease appears less pronounced with SRS compared to WBRT.
Further research is needed to determine the clinical implications of these volumetric changes on survival and neuro-cognitive function.