Related Experiment Video
Updated: Jan 14, 2026
11:15
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
24.9K
Lung carcinoids (lung neuroendocrine tumors): integrated classification, molecular biology, diagnosis, and
Anna Koumarianou1, Jules Derks2, Marina Tsoli3
1Hematology Oncology Unit, Fourth Department of Internal Medicine, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens 12462, Greece.
Endocrine Reviews
|January 12, 2026
Summary
This review synthesizes current knowledge on lung carcinoids, detailing classification, epidemiology, and diagnosis. It outlines evidence-based treatments and emphasizes multidisciplinary management for improved patient outcomes.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Lung carcinoids are rare neuroendocrine tumors requiring specialized management.
- Current understanding necessitates updates on classification, diagnosis, and treatment.
Purpose of the Study:
- To provide a comprehensive synthesis of current knowledge and guidelines on lung carcinoids.
- To emphasize a multidimensional approach for diagnosis and management.
- To highlight future research directions.
Main Methods:
- Narrative review of existing literature and guidelines.
- Analysis of epidemiological trends, risk factors, and molecular hallmarks.
- Integration of diagnostic modalities and treatment strategies.
Main Results:
- Updated classification based on the latest WHO system, emphasizing molecular markers.
- Detailed insights into etiology, carcinogenesis, and clinical presentations, including secretory syndromes.
- Comprehensive overview of diagnostic tools (imaging, molecular pathology) and treatment options (surgery, systemic, locoregional therapies, emerging modalities).
Conclusions:
- Effective lung carcinoid management requires an integrated, multidisciplinary approach.
- Adherence to updated guidelines and utilization of advanced diagnostics are crucial.
- Further research is needed to enhance diagnosis, treatment, and quality of life for patients.
