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Updated: Jan 15, 2026

Image Acquisition Method for the Sonographic Assessment of the Inferior Vena Cava
Published on: January 13, 2023
Incidental Detection of Persistent Left Superior Vena Cava During Lung Perfusion Scan
Sanket Karangutkar1, Lajos Szabados2, Athar Haroon2
1Department of Nuclear Medicine and Molecular Imaging, National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar skarangutkar@hamad.qa.
Persistent left superior vena cava, a congenital anomaly, was incidentally found during lung perfusion scintigraphy for post-COVID-19 hypoxia. This case highlights the importance of adaptive imaging for interpreting unexpected vascular findings in nuclear medicine.
Area of Science:
- Cardiovascular Imaging
- Nuclear Medicine
- Congenital Anomalies
Background:
- Lung perfusion scintigraphy is vital for pulmonary embolism diagnosis.
- Unexpected vascular anomalies can be detected during these scans.
- Persistent left superior vena cava (PLSVC) is a rare congenital anomaly.
Purpose of the Study:
- To report the incidental finding of PLSVC during lung perfusion scintigraphy.
- To illustrate the diagnostic utility of nuclear medicine in identifying vascular anomalies.
- To emphasize the need for adaptive imaging techniques.
Main Methods:
- Lung perfusion scintigraphy was performed in a patient with post-COVID-19 hypoxia.
- Dual-site radiotracer injections were utilized.
- SPECT/CT was employed for confirmation and detailed anatomical assessment.
Main Results:
- Incidental detection of persistent left superior vena cava during lung perfusion scintigraphy.
- PLSVC was confirmed via dual-site injections and SPECT/CT.
- The anomaly can lead to a right-to-left shunt, bypassing pulmonary circulation.
Conclusions:
- Persistent left superior vena cava can be incidentally identified using lung perfusion scintigraphy.
- Nuclear medicine imaging requires adaptive techniques to interpret atypical vascular findings.
- Accurate interpretation is crucial for patient management, especially in cases of hypoxia.
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