Diffuse Annular Plaques in a Man in his 70s.

Area of Science:

• Hematology
• Dermatology
• Oncology

Background:

• Cutaneous manifestations can be the initial sign of hematologic malignancies.
• Diffuse annular plaques are uncommon dermatologic presentations.

Purpose of the Study:

• To highlight the association between specific skin lesions and acute myeloid leukemia (AML).
• To emphasize the importance of considering leukemia in patients with persistent, unusual skin findings.

Main Methods:

• Case presentation of a 70-year-old male with chronic, diffuse annular plaques.
• Diagnostic workup included skin biopsy, bone marrow smear, and bone marrow flow cytometry.

Main Results:

• The patient was diagnosed with acute myeloid leukemia (AML).
• Skin biopsy and bone marrow analyses confirmed the diagnosis.

Conclusions:

• Diffuse annular lesions unresponsive to eczema treatment may signal leukemia.
• Bone marrow examination is crucial for diagnosing hematologic malignancies presenting with dermatologic signs.