Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Introduction to Mechanisms of Enzyme Catalysis

Introduction to Mechanisms of Enzyme Catalysis

For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...

Catalysis

Catalysis

The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...

Metal-Ligand Bonds

Metal-Ligand Bonds

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Discovery of a Robust Single-Atom Ruthenium Emission Control Catalyst.

Angewandte Chemie (International ed. in English)·2026

Same author

Engineering Interfacial Water for Advanced Electrocatalytic CO<sub>2</sub> Reduction: From Molecular Understanding to Materials Design.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Two-dimensional p-π conjugated amide-linked polymeric photocatalysts with enhanced carrier separation.

Nature communications·2026

Same author

Accelerated O─O Bond Cleavage and Stabilized Fe Sites by Synergistic d─p Fe─Sn Dual-Atom Pair for Enhanced Oxygen Reduction.

Angewandte Chemie (International ed. in English)·2026

Same author

Directing robust built-in electric fields <i>via</i> imine linkage orientation in COFs for efficient dehydrogenative organic transformation coupled with H<sub>2</sub>O<sub>2</sub> photosynthesis.

Chemical science·2025

Same author

Built-in Axial Electric Field-Driven Electron-Rich Monomolecular Co Sites for Promoting CO<sub>2</sub> Electroreduction to CO Over Ultrawide Potential Window.

Angewandte Chemie (International ed. in English)·2025

Search research articles

Related Experiment Video

Updated: Jan 15, 2026

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

Designing single-atom catalysts: bridging metal-support interaction and adsorption energy optimization.

Huaizhen Cui^1,2, Jiaqi Zhang¹, Chen Chen¹

¹Engineering Research Center of Advanced Rare Earth Materials, Department of Chemistry, Tsinghua University Beijing 100084 China cchen@mail.tsinghua.edu.cn.

Chemical Science

|January 14, 2026

Summary

Single-atom catalysts show promise for the oxygen evolution reaction (OER). A new framework reveals how tuning metal-support interactions via coordination engineering optimizes catalyst design for sustainable energy.

More Related Videos

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

Related Experiment Videos

Last Updated: Jan 15, 2026

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions

Published on: June 16, 2014

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

Area of Science:

Catalysis
Materials Science
Electrochemistry

Background:

Single-atom catalysts (SACs) are promising for the oxygen evolution reaction (OER).
Current understanding of SAC structure-activity relationships at the atomic scale is incomplete.
Traditional descriptors inadequately explain oxygen intermediate adsorption, hindering catalyst design.

Purpose of the Study:

To introduce a "structure-adsorption" framework for designing SACs.
To clarify how metal-support interactions (MSIs) influence OER activity.
To provide design principles for efficient SACs.

Main Methods:

Review of existing literature on SACs for OER.
Analysis of coordination engineering strategies (spin configuration, axial coordination, atomic distance).
Evaluation of the interplay between orbital hybridization and electrostatic effects.

Main Results:

Metal-support interactions (MSIs) can be tuned via coordination engineering.
Optimal OER activity depends on a balance between orbital hybridization and electrostatic effects.
The "structure-adsorption" framework elucidates structure-activity relationships.

Conclusions:

The "structure-adsorption" framework provides clear design principles for SACs.
Tuning MSIs through coordination engineering is key to enhancing OER performance.
This approach facilitates the development of next-generation SACs for sustainable energy conversion.