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Updated: Jan 15, 2026

Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging

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Published on: April 4, 2013

Thrombus Removal with Magnetically Actuated Micro-Transformers.

Fanan Wei¹, Shifan Zhan¹, Ligang Yao¹

¹School of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, Fujian, China.

Macromolecular Bioscience

|January 14, 2026

Summary

This summary is machine-generated.

A novel magnetically actuated microrobot (MAMT) offers a solution for thrombotic disorders. This reconfigurable robot navigates vessels and fragments thrombi, reducing vascular injury and enhancing treatment safety.

Keywords:

magnetic microrobot magnetothermal effect shape memory structure transformation

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Published on: July 18, 2018

Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Thrombotic disorders are a leading cause of mortality worldwide.
Current medical robots for vascular interventions face limitations like invasiveness, vascular wall stress, and navigation challenges.
Need for flexible yet controllable systems for untethered vascular navigation and treatment.

Purpose of the Study:

To introduce a magnetically actuated microrobot (MAMT) with in situ structural reconfigurability for treating thrombotic disorders.
To demonstrate dual-mode operation for navigation and thrombus fragmentation.
To evaluate the safety and efficacy of the MAMT in simulated vascular environments.

Main Methods:

Fabrication of a microrobot using shape memory polymer (SMP) embedded with Fe3O4 magnetic nanoparticles.
Utilizing magnetothermal effect induced by an alternating magnetic field (AMF) for structural transformation.
Testing structural switching, shape recovery, and thrombus clearance in simulated blood and thrombus environments.

Main Results:

The MAMT demonstrated structural transformation from rod-like to helical shape within 148 ± 8 seconds in a simulated blood environment.
Achieved a shape recovery ratio of 92.11% upon magnetic actuation.
Successfully cleared 52.7% of simulated thrombus, showcasing its fragmentation capability.

Conclusions:

The magnetically actuated microrobot (MAMT) offers a promising, reconfigurable solution for thrombotic disorder treatment.
Dual-mode functionality (navigation and fragmentation) enhances therapeutic potential.
Reduced risk of vascular wall injury and improved safety profile compared to conventional methods.