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Monodentate Transient Directing Group Enabled Distal C─H Bond Functionalization in Ferrocenecarboxaldehyde.

Ashwini Dilip Dhumale1, Devendra Parganiha1, Shilpi Bhardwaj1

  • 1Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India.

Chemistry, an Asian Journal
|January 14, 2026
PubMed
Summary

This study introduces a new method for distal C-H activation using palladium migration, facilitated by a transient directing group. This approach enables efficient heteroannular C-H functionalization of ferrocenecarboxaldehydes.

Keywords:
alkenylationdistal C–H activationferrocenesligand accelerationpalladium catalysis

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