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Updated: May 2, 2026

Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
Recent advances in electrochemical genosensing
Alnilan Lobato1, Mitja Koderman2, Nika Vranešič3
1Department of Analytical Chemistry, National Institute of Chemistry, Ljubljana, Slovenia; International Postgraduate School Jožef Stefan, Ljubljana, Slovenia.
Abstract:
Electrochemical genosensing finds applications across a wide range of fields, including clinical diagnostics, forensic science, food safety, agriculture, biotechnology, cancer research, defense, environmental monitoring, etc. It focuses on the detection of specific DNA or RNA sequences, often called target sequences, rather than target analytes as in conventional (electro)analysis. Since the groundbreaking contributions dating back to the late 1990s and early 2000s, nearly 500 articles have been published elucidating various important aspects of this research field. This review aims to provide an overview of the current state of knowledge, serving as a comprehensive synthesis of the most recent literature on electrochemical genosensors, published in the last five years. Hopefully, it will also serve as a valuable resource for students, young researchers, scientists, non-academics, or other professionals seeking a consolidated understanding of the key aspects behind this research area, without delving into a collection of individual and scattered studies.
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