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Reconstruction of Facial Bony Defects Using 3D Printed Polylactic Acid/β-Tricalcium Phosphate Bioimplant
Shukhrat Boymuradov1, Shokhrukh Yusupov1, Najla Dar-Odeh2
1Tashkent State Medical University, Tashkent, Uzbekistan.
The Journal of Craniofacial Surgery
|January 15, 2026
Summary
This study shows that a 3D-printed poly-L-lactic acid/beta-tricalcium phosphate scaffold effectively treated a complex facial defect. The bioactive scaffold promoted bone regeneration and improved function, demonstrating its potential in reconstructive surgery.
Area of Science:
- Biomaterials science
- Regenerative medicine
- 3D printing in surgery
Background:
- Facial defect reconstruction demands precision and advanced technologies.
- 3D printing, bioactive materials, and AI enhance reconstructive surgery safety and efficiency.
- Biomaterials promote bone regeneration through biocompatibility and osteogenesis.
Purpose of the Study:
- To evaluate the efficacy of a custom-made 3D-printed scaffold for a complex zygomaticomaxillary defect.
- To assess the use of poly-L-lactic acid/beta-tricalcium phosphate (PLA/β-TCP) in trauma reconstruction.
Main Methods:
- Utilized a 3D-printed, custom-made scaffold composed of poly-L-lactic acid/beta-tricalcium phosphate (PLA/β-TCP).
- Applied the scaffold to manage a complex zygomaticomaxillary defect in a trauma patient.
Main Results:
- The 3D-printed PLA/β-TCP scaffold demonstrated efficacy in managing the complex defect.
- The bioactive material facilitated bone tissue formation, strengthening, and interlocking, promoting regeneration and function.
Conclusions:
- 3D-printed custom scaffolds made of PLA/β-TCP are effective for complex facial defect reconstruction.
- Bioactive biomaterials significantly enhance bone regeneration and functional recovery in reconstructive surgery.
