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Pulmonary Metastasis From Glioblastoma: An Uncommon Clinical Entity
María Conejero Merchán1, Rafael D'Ambrosi Centeno2, Beatriz Raboso Moreno1,3
1Department of Pulmonology, Hospital Universitario de Getafe, Madrid, Spain.
Extracranial metastasis from glioblastoma (GBM) is rare, but this case shows pulmonary spread in a patient with sinus invasion. This highlights the need for vigilance regarding systemic symptoms in GBM patients.
Area of Science:
- Neuro-oncology
- Pulmonary Medicine
- Pathology
Background:
- Glioblastoma (GBM) is a high-grade IV primary brain tumor.
- Extracranial metastasis is exceptionally rare (<2%) due to the blood-brain barrier and absent lymphatic drainage.
- Sinus invasion or neurosurgery may increase the risk of GBM metastasis.
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