Epidemiology and Outcomes of Culture-proven Neonatal Meningitis in Australian Tertiary Hospitals: A Multicenter Retrospective Cohort Study
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Natalie Duffy1, Archana Koirala1,2,3, Phoebe C M Williams1,2,3,4
1From the Department of Infectious Diseases, Sydney Children's Hospital Network, Sydney, New South Wales, Australia.
Abstract:
We conducted a 5-year multicenter, retrospective cohort study to describe bacterial meningitis in Australian infants (0-180 days). Of 21 culture-positive infections, Streptococcus agalactiae (29%, 6/21), Staphylococcus aureus (19%, 4/21) and Escherichia coli (19%, 4/21) predominated. Four infants died (19%), including 3 with neurosurgical meningitis. In survivors, neurologic sequelae were common. Novel interventions to reduce the morbidity and mortality burden caused by neonatal meningitis are needed.
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