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Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities

Wentao Li1, Lijun Lv1, Yibin Jin1

  • 1Department of Orthopedic Surgery, The Third Affiliated Hospital of Gansu University of Chinese Medicine, Baiyin, Gansu 730900, P.R. China.

Oncology Reports
|January 16, 2026
PubMed
Abstract

Keywords:
adoptive cell therapybone sarcomaextracellular matrix remodelingimmuno­therapy resistancemyeloid reprogrammingsingle‑cell and spatial omicstumor microenvironment

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