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Updated: Jan 20, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Bone Health Medication Following Low Energy Thoracic and Lumbar Fractures.
Brendan M Striano1, Alexander M Crawford2, Kaitlyn E Holly1
1Department of Orthopaedic Surgery, Mass General Brigham, Harvard Medical School, Boston, MA.
Osteoporosis treatment initiation after low-energy spine fractures is low (10%). Spine surgeon involvement significantly increases the odds of patients receiving bone health medications, improving osteoporosis management.
Area of Science:
- Orthopedics
- Geriatrics
- Pharmacology
Background:
- Low-energy thoracic and lumbar spine fractures in patients aged 50+ indicate osteoporosis and treatment eligibility.
- Current data on osteoporosis treatment rates and influencing factors in these patients is limited.
Purpose of the Study:
- To determine the success rate of anti-osteoporosis treatment initiation in eligible patients with spine fractures.
- To identify factors associated with the successful initiation of bone health treatment.
Main Methods:
- Retrospective cohort study of 409 patients (≥50 years) with Type A spine fractures from low-energy trauma (2015-2021).
- Data abstracted included clinical, radiographic, sociodemographic, and medication details.
- Successful treatment defined as new initiation, addition, or switch of bone health agents within 90 days of injury.
- Bivariate and multivariable logistic regression analyses were used.
Main Results:
- Only 10% (41/409) of patients initiated successful osteoporosis treatment within 90 days.
- Surgical intervention was the sole factor significantly associated with receiving bone health treatment.
- Patients treated surgically had over a 3-fold increased odds of receiving osteoporosis treatment (OR 3.35).
Conclusions:
- Appropriate osteoporosis treatment following low-energy spine fractures is infrequent.
- Active involvement by spine surgeons enhances the likelihood of patients receiving necessary bone health medications.
- This suggests surgeon engagement as a potential scalable intervention to improve osteoporosis care.
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