Related Experiment Video
Updated: Jan 20, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Axillary Approach Mastectomy Without Endoscopic Assistance in Chest Masculinization Surgery
Background:
For gender-affirming mastectomy in patients with gender dysphoria and small/nonptotic breasts, traditional periareolar techniques carry risks of visible scar complications. A scar-minimizing alternative is needed.
Objectives:
The aim of the study was to evaluate the outcomes of a novel nonendoscopic axillary approach mastectomy, aiming to eliminate areolar scars or diminish circumareolar incision while assessing safety and patient satisfaction.
Methods:
This study included patients classified with Fisher 1, 2A, and a portion of 2B patients. Mastectomy was performed through an axillary incision without endoscopic assistance. Outcomes were evaluated through complication rates and patient-reported outcomes using the BODY-Q questionnaire (score 0-100).
Results:
From December 2020 to August 2024, 48 patients (average age 33.65) underwent the procedure. The average operative time was 167.1 min. The overall complication rate was 45.8% (22/48), predominantly minor, reversible nipple-areola superficial skin necrosis (20.8%). Severe complications were rare: total NAC necrosis 2.0% (1/48) and acute hematoma 2.0% (1/48). Patient satisfaction on the BODY-Q scale was statistically very high.
Conclusions:
This axillary approach for mastectomy successfully prioritizes minimal scarring, a key aesthetic concern particularly for East Asian patients. In a carefully selected cohort, it achieves high patient satisfaction with a low rate of severe complications, offering a valuable surgical alternative.
Level Of Evidence: 4 (Therapeutic):
For image description, please refer to the figure legend and surrounding text.
Related Concept Videos
13:35Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
05:10Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
08:47Endoscopic Cholesteatoma Surgery
02:37Robot-Assisted Transcanal Endoscopic Ear Surgery for Congenital Cholesteatoma
07:43Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
02:21Radical Mastectomy: Surgical Removal of the Entire Mammary Gland from a Mouse to Study Cancer Progression

