Related Experiment Video
Updated: Jan 20, 2026
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Preoperative neutrophil-to-lymphocyte ratio and refracture risk in hip fracture patients: a propensity score-matched
1Department of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital, Soochow University, Suzhou, China.
Background:
The relationship between preoperative neutrophil-to-lymphocyte ratio (NLR) and refracture risk in hip fracture patients remains unclear.
Methods:
This retrospective study included 701 patients with hip fractures between 2018 and 2020. Multivariate logistic regression and propensity score matching (PSM) assessed the association between preoperative NLR (analysed as a continuous variable) and refracture risk, adjusting for age, sex, comorbidities, fracture characteristics and laboratory parameters. Subgroup and dose-response analyses evaluated robustness.
Results:
Refracture occurred in 119 patients (16.98%). Each unit increase in NLR (as a continuous variable) was associated with 8.0% increased refracture odds (odds ratio (OR) = 1.080, 95% confidence interval (CI) = 1.019-1.144, p = 0.009). PSM confirmed this association (crude OR = 1.119, p = 0.006; adjusted OR = 1.108, p = 0.014). The association remained consistent across patient subgroups (all p for interaction > 0.05) with a linear dose-response relationship.
Conclusions:
Elevated preoperative NLR independently predicts refracture risk in hip fracture patients. This readily available biomarker may facilitate risk stratification and guide prevention strategies.
More Related Videos
15:11Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
Published on: January 5, 2015
06:58Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
Published on: August 17, 2017
Related Concept Videos
06:55Inverse Probability of Treatment Weighting (Propensity Score) using the Military Health System Data Repository and National Death Index
15:11Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
06:58Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
09:59Hip Exam
The hip is a ball-and-socket joint that consists of the femoral head articulating with the acetabulum. When combined with the hip ligaments, the hip makes for a very strong and stable joint. But, despite this stability, the hip has considerable motion and is prone to degeneration with wear and tear over time and after injury. Hip pain can affect patients of all ages and can be associated with various intra- and...
09:02Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
08:23An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes