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Updated: Jan 20, 2026

4D Microscopy of Yeast
Published on: April 28, 2019
4D Lips Technique Based on Anatomy for Naturalization
Melina Kichler1, Marta Barros1, Carolina de Freitas1
1From the Independent Researcher, São Paulo, Brazil.
Background:
Lip augmentation has become a cornerstone of aesthetic procedures, particularly among younger patients seeking to enhance their natural lip features. A precise anatomical approach is essential to achieve balanced, natural-looking results while minimizing the risk of complications. This study introduced the 4D Lips technique, a multiphasic hyaluronic acid filler method designed to enhance lip shape while respecting anatomical landmarks. The technique is guided by 4 fundamental principles-dimension, distribution, dynamics, and desire-to ensure harmonious and individualized outcomes.
Methods:
Ten female patients underwent lip augmentation using a combination of subtechniques, including tubercle marking, vertical elongation, and vermilion border eversion. Two hyaluronic acid fillers with distinct viscoelastic properties were used: one with medium G' for structural support and another with low G' for contour refinement. Patient satisfaction and safety outcomes were systematically evaluated.
Results:
All patients reported satisfaction with the natural appearance of their enhanced lips. Mild and transient side effects, such as swelling, were observed and resolved spontaneously within a few days. No major complications were recorded. The structured, anatomy-based approach allowed for precise volumization, refined contouring, and preservation of natural lip dynamics.
Conclusions:
The 4D Lips technique underscores the value of an anatomy-informed and personalized approach to lip augmentation. By combining structural enhancement with a patient-centered perspective, this method achieves high satisfaction rates and a favorable safety profile. Nonetheless, the limitations of the study, including the small sample size, absence of a control group, and lack of long-term follow-up, warrant further investigation to validate these findings.
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