Multidisciplinary care of pediatric obesity and its impact on sleep: a review

Ravali Inja1, Christopher Cielo1

  • 1Division of Pulmonary and Sleep Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.

Frontiers in Sleep
|January 19, 2026
PubMed

Insights

Pediatric obesity impacts sleep health, leading to conditions like obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS). Multidisciplinary care and further research on treatments like GLP-1 agonists are crucial for managing these complex issues.

Area of Science:

  • Pediatric Endocrinology
  • Sleep Medicine
  • Public Health

Background:

  • Pediatric obesity is a growing global health concern with serious sleep-related comorbidities.
  • Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are common in obese children, affecting quality of life and increasing cardiovascular risks.
  • These conditions often co-occur with insulin resistance, type 2 diabetes, hypertension, and non-alcoholic fatty liver disease (NAFLD).

Purpose of the Study:

  • To review the importance of multidisciplinary care for pediatric obesity.
  • To highlight the role of early diagnosis, lifestyle interventions, and pharmacologic therapies.
  • To discuss the limited data on newer treatments like GLP-1 receptor agonists and bariatric surgery for sleep disorders in children.

Main Methods:

  • Literature review focusing on pediatric obesity and its sleep-related comorbidities.
  • Exploration of multidisciplinary care strategies including nutritional, physical activity, and psychological support.
  • Analysis of current and emerging pharmacologic and surgical interventions.

Main Results:

  • Multidisciplinary care is essential for addressing pediatric obesity and its associated health issues.
  • Pharmacologic therapies like GLP-1 receptor agonists show promise but require more pediatric data.
  • Surgical interventions and newer drug data are limited regarding their impact on sleep disorders.

Conclusions:

  • Effective management of pediatric obesity requires a comprehensive, multidisciplinary approach.
  • Further research is needed to understand the long-term effects of GLP-1 receptor agonists and bariatric surgery on sleep, cognition, and wellbeing in obese children.
  • Evidence-based strategies are vital for improving health outcomes in pediatric obesity.

Related Concept Videos

Multidisciplinary Approach to Obesity Management: A Case Report05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Obesity care is best delivered after in-depth initial screening and evaluation, using an individualized approach comprising multidisciplinary care, evidence-based lifestyle behavioral change strategies, and frequent follow-up. We illustrate a successful 6 month course of weight loss treatment, resulting in reversal of obesity-related chronic conditions and improvement in diet, sleep, mood, and physical fitness.
922
Point-of-Care Ultrasound: A Review of Ultrasound Parameters for Predicting Difficult Airways08:21

Point-of-Care Ultrasound: A Review of Ultrasound Parameters for Predicting Difficult Airways

A point-of-care ultrasound (POCUS) is a simple, non-invasive, and portable tool that enables dynamic airway assessment. Several studies have attempted to determine the role of ultrasound parameters as an adjunct to clinical examination in predicting difficult...
2.3K
Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes08:30

Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes

The incidence of obesity is rising and increases the risk of chronic lung diseases. To establish the underlying mechanisms and preventive strategies, well-defined animal models are needed. Here, we provide three methods (glucose-tolerance-test, body plethysmography, and lung fixation) to study the effect of obesity on pulmonary outcomes in...
14.7K
Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

The goal of this protocol is to showcase the technique and use of point-of-care transient elastography for pediatric gastroenterologists monitoring hepatobiliary involvement and advanced cystic fibrosis liver disease in persons with cystic fibrosis.
442
Quantitative Measurement of the Immune Response and Sleep in Drosophila12:16

Quantitative Measurement of the Immune Response and Sleep in Drosophila

To understand a link between the immune response and behavior, we describe a method to measure locomotor behavior in Drosophila during bacterial infection as well as the ability of flies to mount an immune response by monitoring survival, bacterial load, and real-time activity of a key regulator of innate immunity,...
15.9K
Polygraphic Recording Procedure for Measuring Sleep in Mice08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

The recording of electroencephalogram (EEG) and electromyogram (EMG) in freely behaving mice is a critical step to correlate behavior and physiology with sleep and wakefulness. The experimental protocol described herein provides a cable-based system for acquiring EEG and EMG recordings in...
25.2K