Related Experiment Video
Updated: Jan 20, 2026
Dialysis: Diffusion Based Separation
Published on: April 30, 2023
Impact of Lupus on All-Cause, Cardiovascular, and Infection-Related Mortality Among Dialysis Patients: Okinawa
Nanako Oshiro1, Yukiko Hasuike2, Kentaro Kohagura1
1Dialysis Unit, University Hospital of the Ryukyus, Okinawa, Japan.
Introduction:
Lupus nephritis is one of the most serious complications of systemic lupus erythematosus (SLE) and can lead to end-stage kidney disease (ESKD). We aimed to assess the relative mortality risk associated with SLE among dialysis patients.
Methods:
This retrospective longitudinal cohort study included all dialysis patients in the Okinawa Dialysis Study 30 registry. Cox proportional hazard models were performed to assess mortality.
Results:
Of 5246 patients, 111 had ESKD secondary to SLE. Compared with ESKD patients secondary to other causes, those with SLE had significantly higher risk of death (HR 2.55, 95% CI 1.81-3.47, p < 0.0001), cardiovascular death (HR 1.94, 95% CI 1.13-3.33, p = 0.0158), and infection death (HR 4.21, 95% CI 2.40-7.37, p < 0.0001) after adjusting for age, era of dialysis initiation, and sex.
Conclusion:
SLE may be independently associated with an increased risk of death in dialysis patients.
More Related Videos
Related Concept Videos
Dialysis
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis: Diffusion Based Separation
This video covers the principles of dialysis along with a general procedure. Several applications of dialysis are reviewed, including the removal of gradient...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
06:27A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Peritoneal Dialysis I: Introduction and Procedure