Related Experiment Video
Updated: Jan 20, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Ultra-Sensitive Detection of Bone Metastasis From Accessory Breast Cancer Using HER2 PET/CT: A Case Report
Lei Yang1, Dongling Zhu, Shuang Song
1Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology.
None:
We presented the imaging findings of 18 F-FDG and 68 Ga-HER2 affibody PET/CT in a 52-year-old woman with HER2-positive accessory breast cancer in the right axilla. 18 F-FDG and HER2 PET/CT showed avid uptake of multiple axillary lesions. HER2 PET/CT identified extensive bone metastases with intense uptake, while the ⁹⁹ᵐTc-MDP whole bone scan was negative, and only a few bone lesions with mild tracer uptake were detected by 18 F-FDG PET/CT. Following 6 cycles of the TCbHP regimen, the axillary lesions markedly reduced. This case demonstrates that HER2 PET/CT enables more sensitive detection of HER2-positive lesions, thereby allowing for precise staging and guiding HER2-targeted therapy.
Related Concept Videos
10:28Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
11:34Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers
08:49Models of Bone Metastasis
05:02Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells
09:53Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies
08:11An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis

