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Updated: Jan 21, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
Published on: February 7, 2014
Association Between Healthy Lifestyle Index Trajectories and Functional Disability in Middle-Aged and Older Adults: A
Yue Hu1, Chuanyun Sun1, Jiaxin Gu1
1School of Nursing and Rehabilitation, Shandong University, Jinan, China.
Objective:
To explore the trajectories of combined healthy lifestyle index (HLI), and to examine the association between HLI at a single point, HLI trajectories, and new-onset functional disability among middle-aged and older adults.
Design:
A longitudinal cohort study. Group-based trajectory modeling and binomial logistic regression analysis were used to explore HLI trajectories and their associations with functional disability.
Setting:
Data were obtained from the China Health and Retirement Longitudinal Survey (2011-2020), a nationally representative assessment of community-dwelling middle-aged and older adults spanning 150 counties across 28 provinces.
Participants:
A total of 5985 community-dwelling individuals aged ≥45 years were included for cross-sectional analysis, 3213 of whom were women. In addition, 3888 individuals without functional disability at baseline were eligible for the longitudinal analysis.
Interventions:
Not applicable.
Main Outcome Measures:
Activities of daily living (ADLs) disability and instrumental activities of daily living (IADLs) disability.
Results:
Three distinct HLI trajectories were identified: persistently high-level then declining group (n=742, 19.08%), persistently moderate-level then declining group (n=2416, 62.14%), and persistently low-level group (n=730, 18.78%). In comparison with persistently low-level group, persistently high-level then declining group was associated with a lower risk of ADL disability (odds ratio [OR], 0.40; 95% confidence interval [CI], 0.23-0.67) and IADLs disability (OR, 0.51; 95% CI, 0.36-0.73), whereas persistently moderate-level then declining group only had a lower risk of ADL disability (OR, 0.70; 95% CI, 0.50-1.00).
Conclusions:
The healthy lifestyle was stable and not susceptible to prolonged change without external influences. Sustaining the high level of healthy lifestyle benefited functional capacity in middle-aged and older adults. Future research needs to focus on improving the overall lifestyle intervention to maximize the effectiveness of the intervention.
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