Outcome in Patients with Secundum Type Atrial Septal Defect Referred for Percutaneous or Surgical Closure: A
Johanna Gorenflo1, Victoria Ziesenitz2, Mina Farag3
1University Medical Centre Mannheim, Ear, Nose and Throat Department, Mannheim, Germany.
The Thoracic and Cardiovascular Surgeon
|January 19, 2026
Summary
This study shows that both surgical and transcatheter closure of Atrial Septal Defects (ASD) are safe and effective. Echocardiography helps determine the best closure method for patients with ASD.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Atrial Septal Defects (ASD) are common congenital heart abnormalities.
- Treatment options for ASD include surgical repair and transcatheter device closure.
- Choosing the optimal closure method is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the safety and efficacy of both surgical and interventional closure of Atrial Septal Defects (ASD).
- To compare outcomes between surgical and transcatheter closure methods for ASD.
- To assess the role of echocardiography in guiding the choice of ASD closure procedure.
Main Methods:
- Retrospective analysis of 611 patients undergoing ASD closure.
- Data collected on patient demographics, procedural details, and follow-up outcomes.
- Comparison of outcomes between intracardiac repair (surgical) and transcatheter device closure (interventional).
Main Results:
- No in-hospital mortality observed in either surgical or interventional groups.
- Transcatheter device closure was successful in a high percentage of attempted cases.
- Complete normalization of right ventricular dimensions occurred in a significant portion of patients post-closure.
- Complications included device erosion, dislocation, and persistent atrial fibrillation in a small number of patients.
Conclusions:
- Both surgical and interventional closure of ASD are safe and effective treatment options.
- Pre-operative echocardiography is valuable in selecting the appropriate closure strategy.
- Transcatheter device closure offers a viable alternative to surgical repair for many ASD patients.
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