Unique One-Stage Procedure: Simultaneous Patent Foramen Ovale Closure and Resection of Wilms Tumor With Vena Cava...

Wilms tumor with intravascular extension poses significant surgical challenges, particularly when combined with a patent foramen ovale, which adds the risk of paradoxical embolism. We report the first case hitherto reported of a 5-year-old boy successfully treated in a single-stage procedure combining surgical PFO closure, nephrectomy, and inferior vena cava thrombectomy. The child recovered uneventfully and remains without complications and tumor-free at 6-month follow-up. This case highlights the importance of thorough preoperative assessment in nephroblastoma patients and demonstrates the value of interdisciplinary collaboration in managing rare and complex pediatric oncologic scenarios.