Local Acidic Microenvironments Enhanced Anodic Formamide Electrosynthesis over Isolated Pd Sites
Baian Shen1, Ming Jiang2, Yaoxin Li1
1Institute of Molecular Plus, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300354, China.
Angewandte Chemie (International Ed. in English)
|January 20, 2026
Summary
Sustainable formamide synthesis is advanced using palladium single atoms on manganese dioxide nanoarrays. This method boosts efficiency and selectivity for electrocatalytic C-N coupling reactions under ambient conditions.
Area of Science:
- Electrochemistry
- Catalysis
- Sustainable Chemistry
Background:
- Electrocatalytic C-N coupling for formamide synthesis faces challenges in selectivity and efficiency.
- Optimizing intermediates' electrophilicity and preventing over-oxidation are key for improved performance.
Purpose of the Study:
- To develop an efficient electrocatalyst for sustainable formamide synthesis.
- To investigate mechanisms enhancing C-N coupling selectivity and Faradaic efficiency.
Main Methods:
- Anchoring palladium (Pd) single atoms onto manganese dioxide (MnO2) nanoarrays.
- Employing in situ characterization and theoretical simulations to analyze catalytic mechanisms.
Main Results:
- Achieved state-of-the-art Faradaic efficiency (62.6%) and carbon selectivity (80.2%) for anodic formamide synthesis.
- Identified dual enhancement mechanisms involving Pd single sites and MnO2-induced acidic microenvironment.
Conclusions:
- Pd single atoms on MnO2 nanoarrays significantly improve formamide synthesis efficiency.
- Synergistic effects enhance electrophilicity of key intermediates and promote C-N coupling.
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