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Assessment of Sleep-Disordered Breathing and Sleep Quality in Childhood Interstitial Lung Disease: A Single-Center
Sinem Can Oksay1, Özge Ülgen1, Yadigar Öztürk1
1Department of Pediatrics, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, Division of Pediatric Pulmonology, Istanbul, Türkiye.
Insights
Sleep-disordered breathing (SDB) is common in children with interstitial lung disease (chILD), affecting sleep quality. Polysomnography and questionnaires are recommended for screening and detection in chILD patients.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
Background:
- Adult interstitial lung disease (ILD) patients often have poor sleep quality and sleep-disordered breathing (SDB).
- The impact of chILD on sleep quality and SDB prevalence is understudied.
Purpose of the Study:
- To assess sleep quality and SDB prevalence in children with ILD.
- To explore associations between SDB and clinical, functional, and radiological parameters in chILD.
Main Methods:
- Prospective cross-sectional study of children diagnosed with ILD.
- Collected sleep questionnaire data and polysomnography (PSG) parameters.
- Compared SDB outcomes between patients with and without lung fibrosis.
Main Results:
- 77% of 30 chILD patients had obstructive sleep apnea syndrome (OSAS).
- 80% reported impaired sleep quality, and 60% had an increased SDB risk via questionnaires.
- Reduced REM sleep occurred in 90% of patients; no significant association between pulmonary fibrosis and SDB was found.
Conclusions:
- Sleep-disordered breathing (SDB) is prevalent in chILD, contrary to prior assumptions.
- Utilizing PSG and sleep questionnaires is crucial for improved screening and detection of SDB in chILD.
- Early identification and management of SDB can potentially improve sleep quality in children with ILD.
Background:
While adult patients with interstitial lung disease (ILD) commonly experience poor sleep quality characterized by abnormal sleep architecture, increased fragmentation, and sleep-disordered breathing (SDB), children's interstitial lung disease (chILD)-a heterogeneous group of diffuse parenchymal lung diseases-remains less studied in terms of its impact on sleep.
Objective:
We aimed to assess sleep quality and the prevalence of SDB, and to investigate potential associations between SDB and clinical, functional, and radiological parameters.
Materials And Methods:
This prospective cross-sectional study included children diagnosed with ILD. Sleep questionnaire scores, polysomnography (PSG) parameters, and SDB outcomes were recorded and compared between patients with and without lung fibrosis.
Results:
Of 30 patients (36.7% female, mean age 115 ± 59.3 months), 77% were diagnosed with OSAS (63.3% mild, 13.3% moderate). Sleep efficiency was below 85% in 20% of cases, and REM sleep was reduced in 90%. Median AHI was 1.8. According to sleep questionnaires, 80% of patients had impaired sleep quality, and 60% showed an increased risk for SDB. No significant association was found between pulmonary fibrosis and SDB.
Conclusion:
Contrary to common belief, SDB is not rare in chILD, and PSG alongside sleep questionnaires should be used in follow-up to improve screening and detection.
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