Related Experiment Video
Updated: Jan 22, 2026

Establishment of a Co-culture System of Patient-Derived Colorectal Tumor Organoids and Tumor-Infiltrating Lymphocytes (TILs)
Published on: June 27, 2025
[Thyroglobulin - An important tumor marker and laboratory challenge]
Eleonore Fröhlich1,2, Richard Wahl2
1Zentrum für Medizinische Forschung, Medizinische Universität Graz, Graz, Österreich.
Abstract:
Serum/plasma thyroglobulin (TG) levels and neck ultrasonography are currently the mainstay of postoperative monitoring in patients with differentiated thyroid cancer (DTC). TG can be determined as a tumor marker in these patients under required levothyroxine treatment at TSH suppressive doses. The immunologic determination of TG as a laboratory parameter in the follow-up of thyroid malignancies always requires confirmation of the test result in order to detect interfering variables. There are two commonly used options: first, the TG recovery rate and second, the determination of anti-TG autoantibodies (TGAb). However, neither test adequately addresses the issue of correct TG determination. Heterophilic antibodies are another important source of interference. Mass spectroscopic TG determination is a more complex alternative that can be used in inconclusive cases.
Related Concept Videos
Serum Laboratory Studies, Stool Test, Breath Test
Tumor Immunotherapy
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
The Tumor Microenvironment
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Cancer Stem Cells and Tumor Maintenance
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...

