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Updated: Jan 22, 2026

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Root Coverage of Multiple Gingival Recessions using Leukocyte- and Platelet-rich Fibrin Associated with Coronally
Thaissa Cavalcante Vieira Bitu1, Natacha Malu Miranda Da Costa2, Rafael Linard Avelar1
1Department of Dentistry, Christus University Center, Fortaleza, Ceara, Brazil.
Abstract:
Periodontal plastic surgery is constantly seeking alternatives that can replace the use of connective tissue grafts, due to the need for a second surgical area and the possibility of reducing the morbidity of the procedure and providing better comfort to the patient. The use of leukocyte- and platelet-rich fibrin (L-PRF) in the treatment of gingival recessions (GRs) has been studied and its potential has been observed. We report a clinical case of a 49-year-old female patient, a non-smoker, with hypothyroidism and multiple gingival recessions (GRs) in the anterior teeth classified as Miller Class I or Cairo Type 1 (RT1-), which are not associated with a non-carious cervical lesion. The patient presented with aesthetic discomfort and dentin hypersensitivity. Root coverage of the recessions was performed with L-PRF membranes associated with a coronally advanced flap. After 8 months of follow-up, we observed complete coverage of the exposed roots, thickness keratinized gingiva gain, and patient satisfaction with gingival esthetics and dentin hypersensitivity.
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