Related Experiment Video
Updated: Jan 23, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
Geschwind syndrome in remitted bipolar affective disorder without MRI brain findings: A case report
Ilambaridhi Balasubramanian1, Priya Sarkar1, Sahanavarshini Ravi1
1Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Abstract:
Geschwind Syndrome (GS) comprises a constellation of behavioural traits traditionally associated with temporal lobe epilepsy. These include hyper-religiosity, hypergraphia, altered sexuality, and circumstantial thought processes. Increasingly, GS features are also observed in other neuropsychiatric conditions. We present a 26-year-old female with bipolar affective disorder in remission who developed GS-like features such as hyper-religiosity, compulsive writing, and atypical romantic ideation, without evidence of seizures, abnormal EEG, or MRI findings. She showed limited response to aripiprazole and partial improvement with behavioural interventions. This case highlights the need for increased recognition of GS features in psychiatric populations, independent of structural or seizure-related pathology.
Related Concept Videos
Bipolar Disorder
Role of Affect in Interpersonal Attraction
The Influence of Affect on Cognition
The Influence of Cognition on Affect
Bipolar Junction Transistor
Finding the Center of Gravity

