Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Quantum Numbers02:43

Quantum Numbers

49.4K
It is said that the energy of an electron in an atom is quantized; that is, it can be equal only to certain specific values and can jump from one energy level to another but not transition smoothly or stay between these levels.
49.4K
The Quantum-Mechanical Model of an Atom02:45

The Quantum-Mechanical Model of an Atom

56.7K
Shortly after de Broglie published his ideas that the electron in a hydrogen atom could be better thought of as being a circular standing wave instead of a particle moving in quantized circular orbits, Erwin Schrödinger extended de Broglie’s work by deriving what is now known as the Schrödinger equation. When Schrödinger applied his equation to hydrogen-like atoms, he was able to reproduce Bohr’s expression for the energy and, thus, the Rydberg formula governing hydrogen spectra.
56.7K
Resonance02:52

Resonance

64.8K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
64.8K
Spin–Spin Coupling Constant: Overview01:08

Spin–Spin Coupling Constant: Overview

1.5K
In bromoethane, the three methyl protons are coupled to the two methylene protons that are three bonds away. In accordance with the n+1 rule, the signal from the methyl protons is split into three peaks with 1:2:1 relative intensities. The methylene protons appear as a quartet, with the relative intensities of 1:3:3:1.
Qualitatively, any spin plus-half nucleus polarizes the spins of its electrons to the minus-half state. Consequently, the paired electron in the hydrogen–carbon bond must...
1.5K
NMR Spectroscopy: Spin–Spin Coupling01:08

NMR Spectroscopy: Spin–Spin Coupling

3.0K
The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
3.0K
Spin–Spin Coupling: One-Bond Coupling01:17

Spin–Spin Coupling: One-Bond Coupling

1.4K
Coupling interactions are strongest between NMR-active nuclei bonded to each other, where spin information can be transmitted directly through the pair of bonding electrons. While nuclei polarize their electrons to the opposite spins, the bonding electron pair has opposite spins. Configurations with antiparallel nuclear spins are expected to be lower in energy. When coupling makes antiparallel states more favorable, J is considered to have a positive value. The one-bond coupling constant, 1J,...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring brain glucose metabolism in multiple sclerosis: A deuterium metabolic imaging study.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2026
Same author

Magnetic resonance control of spin-correlated radical pair dynamics in vivo.

Nature·2026
Same author

Photoinduced Spin Polarization of a Gadolinium Complex.

Journal of the American Chemical Society·2026
Same author

Spin-Dependent Photoluminescence in Carbon-Based Quantum Dots.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Introduction to modeling radical pair quantum spin dynamics with tensor networks.

The Journal of chemical physics·2026
Same author

Efficient and Robust p-Type Transistor Based on Ultrawide-Bandgap Semiconductor.

ACS nano·2026

Related Experiment Video

Updated: Jan 23, 2026

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
12:19

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

8.8K

Quantum spin resonance in engineered proteins for multimodal sensing.

Gabriel Abrahams1, Ana Štuhec2, Vincent Spreng3,4

  • 1Department of Engineering Science, University of Oxford, Oxford, UK. gabriel.abrahams@eng.ox.ac.uk.

Nature
|January 21, 2026
PubMed
Summary

Engineered magneto-sensitive fluorescent proteins, like MagLOV, enable quantum sensing in living cells. These proteins allow for high-resolution bio-imaging and molecular sensing at room temperature.

More Related Videos

Quantum State Engineering of Light with Continuous-wave Optical Parametric Oscillators
09:23

Quantum State Engineering of Light with Continuous-wave Optical Parametric Oscillators

Published on: May 30, 2014

15.0K
Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

9.6K

Related Experiment Videos

Last Updated: Jan 23, 2026

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
12:19

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

8.8K
Quantum State Engineering of Light with Continuous-wave Optical Parametric Oscillators
09:23

Quantum State Engineering of Light with Continuous-wave Optical Parametric Oscillators

Published on: May 30, 2014

15.0K
Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

9.6K

Area of Science:

  • Quantum sensing
  • Biotechnology
  • Protein engineering

Background:

  • Quantum sensing technologies are increasingly applied in various scientific fields.
  • Previous biological quantum sensors were limited to in vitro systems, lacking sensitivity and stability.
  • These limitations hindered practical biotechnological applications and high-throughput engineering.

Purpose of the Study:

  • To engineer magneto-sensitive fluorescent proteins for enhanced quantum sensing in biological systems.
  • To demonstrate optically detected magnetic resonance (ODMR) in living bacterial cells using engineered proteins.
  • To explore novel bio-imaging and sensing applications based on quantum phenomena.

Main Methods:

  • Directed evolution of magneto-sensitive fluorescent proteins (e.g., MagLOV).
  • Optically Detected Magnetic Resonance (ODMR) measurements in living bacterial cells at room temperature.
  • Fluorescence magnetic-field effects analysis and application demonstrations.

Main Results:

  • Engineered MagLOV proteins exhibit ODMR in living bacteria with high signal-to-noise for single-cell detection.
  • The radical-pair mechanism involving protein backbone and flavin cofactor explains the observed effects.
  • Demonstrated applications include genetically encoded magnetic resonance imaging, microenvironment sensing, and multiplexed bio-imaging.

Conclusions:

  • Magneto-sensitive fluorescent proteins can be engineered for robust quantum sensing in living biological systems.
  • These engineered proteins offer novel modalities for bio-imaging and molecular sensing, overcoming traditional limitations.
  • The study provides a suite of sensing tools for engineered biological systems leveraging quantum mechanics.