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Assessment of Pathtezt® Infinity Processor and Autoloader Efficiency in Cervical Smear Analysis.

Nur Syuhada Mohd Nafis1,2, Anani Aila Mat Zin1,2, Siti Azrin Ab Hamid3

  • 1Department of Pathology, School of Medical Science, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Asian Pacific Journal of Cancer Prevention : APJCP
|January 22, 2026
PubMed
Summary

The PathTezt® Infinity with Autoloader produces high-quality cervical cancer screening smears with 97.7% overall good performance. This automated system is effective and suitable for widespread use in cytological evaluations.

Keywords:
Cost effectivenessLiquid-based cervical smearPath Tezt Processor

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Area of Science:

  • Cytopathology
  • Medical Device Technology
  • Public Health

Background:

  • Cervical cancer screening relies on the quality of cytological smears.
  • Automated systems aim to improve efficiency and consistency in slide preparation.

Purpose of the Study:

  • To evaluate the quality of cervical cytological smears generated by the PathTezt® Infinity with Autoloader.
  • To assess key parameters including cellularity, epithelial cell coverage, arrangement, preservation, and interfering factors.

Main Methods:

  • 1003 Pap smear samples were processed using the PathTezt® Infinity with Autoloader.
  • Slides were analyzed for smear adequacy, cellular coverage, arrangement, preservation, and obscuring factors.

Main Results:

  • 94.1% of samples were adequate for evaluation.
  • 85.7% showed good cellular arrangement, and 94.7% had minimal obscuration by inflammatory cells.
  • The overall "good" performance rate was 97.7%.

Conclusions:

  • The PathTezt® Infinity with Autoloader yields high-quality cervical smears.
  • The system is user-friendly, automated, and cost-effective.
  • It is a suitable tool for cervical cancer screening programs.