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Assessment of Pathtezt® Infinity Processor and Autoloader Efficiency in Cervical Smear Analysis
Nur Syuhada Mohd Nafis1,2, Anani Aila Mat Zin1,2, Siti Azrin Ab Hamid3
1Department of Pathology, School of Medical Science, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Asian Pacific Journal of Cancer Prevention : APJCP
|January 22, 2026
Summary
The PathTezt® Infinity with Autoloader produces high-quality cervical cancer screening smears with 97.7% overall good performance. This automated system is effective and suitable for widespread use in cytological evaluations.
Area of Science:
- Cytopathology
- Medical Device Technology
- Public Health
Background:
- Cervical cancer screening relies on the quality of cytological smears.
- Automated systems aim to improve efficiency and consistency in slide preparation.
Purpose of the Study:
- To evaluate the quality of cervical cytological smears generated by the PathTezt® Infinity with Autoloader.
- To assess key parameters including cellularity, epithelial cell coverage, arrangement, preservation, and interfering factors.
Main Methods:
- 1003 Pap smear samples were processed using the PathTezt® Infinity with Autoloader.
- Slides were analyzed for smear adequacy, cellular coverage, arrangement, preservation, and obscuring factors.
Main Results:
- 94.1% of samples were adequate for evaluation.
- 85.7% showed good cellular arrangement, and 94.7% had minimal obscuration by inflammatory cells.
- The overall "good" performance rate was 97.7%.
Conclusions:
- The PathTezt® Infinity with Autoloader yields high-quality cervical smears.
- The system is user-friendly, automated, and cost-effective.
- It is a suitable tool for cervical cancer screening programs.
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