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Updated: Jan 23, 2026

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
Published on: September 17, 2021
[Hidden danger: a tare cause of painful muscle spasms after long-lie]
Barbara Schürch1, Cédric Hirzel2, Claudine Kocher3
1Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland.
Introduction:
The introduction of systematic vaccination programs since the 1940s has led to a significant reduction in prevalence of tetanus in Western countries. However, tetanus cases still occur sporadically, especially in older people with inadequate immunisation status. The diagnosis is primarily clinical. Microbiological isolation of the gram-positive, anaerobic rod-shaped bacteria is often unsuccessful (not necessarily required for diagnosis). Specific treatment includes wound debridement, administration of tetanus immunoglobulin, tetanus vaccination and antibiotic therapy. Moreover, supportive measures up to invasive ventilation are used.
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