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Abdominal vascular imaging with ferumoxytol - how we do it
Mitchell A Rees1,2, Rida Salman3, Rajesh Krishnamurthy3,4
1Department of Radiology, Nationwide Children's Hospital, ED Bldg 4th Floor, 700 Children's Drive, Columbus, OH 43205, United States. mitchell.rees@nationwidechildrens.org.
Pediatric Radiology
|January 22, 2026
Summary
Ferumoxytol-enhanced MR angiography offers high-resolution pediatric abdominal vessel imaging. This iron-based agent is a safe alternative for patients with gadolinium contraindications, useful in various abdominal conditions.
Area of Science:
- Radiology
- Pediatric Imaging
- Vascular Imaging
Background:
- Ferumoxytol is an iron-based blood pool contrast agent for MR angiography.
- It provides high-resolution imaging independent of contrast timing.
- It is an alternative for patients with gadolinium contraindications.
Purpose of the Study:
- To review the protocol for ferumoxytol-enhanced MR angiography in pediatric patients.
- To discuss the applications of ferumoxytol-enhanced MR angiography in pediatric abdominal conditions.
Main Methods:
- Review of institutional experience and literature.
- Description of ferumoxytol-enhanced MR angiography protocol.
- Discussion of clinical applications.
Main Results:
- Ferumoxytol-enhanced MR angiography is effective for pediatric abdominal vasculature.
- Applications include portal hypertension, portosystemic shunts, transplant evaluation, vascular malformations, vasculitis, and hepatic tumors.
- High-resolution imaging is achieved without strict phase timing.
Conclusions:
- Ferumoxytol-enhanced MR angiography is a valuable tool for pediatric abdominal vascular imaging.
- It expands imaging options for children with contraindications to gadolinium-based contrast agents.
- Its utility spans diverse abdominal vascular pathologies.
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