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Case report: Ulocladium spp. (mold) catheter-related peritoneal dialysis-associated peritonitis

Remington E Schmidt1, Megan Bernabe1, Kamran N Azad2

  • 1Dept. of Nephrology, MercyCare, Cedar Rapids, IA, USA.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|January 22, 2026
PubMed

Insights

Fungal peritonitis from Ulocladium, a rare cause of peritoneal dialysis peritonitis, was successfully treated. Early antifungal treatment and catheter removal improved patient outcomes.

Area of Science:

  • Nephrology
  • Mycology
  • Infectious Diseases

Background:

  • Peritoneal dialysis (PD)-associated peritonitis is a significant complication of PD.
  • Fungal PD peritonitis presents a high risk of morbidity and mortality.
  • Ulocladium, a filamentous fungus, has not been previously reported as a cause of PD peritonitis.

Purpose of the Study:

  • To report a unique case of PD peritonitis caused by Ulocladium.
  • To emphasize the importance of recognizing and treating fungal PD peritonitis.

Main Methods:

  • A case report of a 65-year-old female patient undergoing PD.
  • Clinical presentation, diagnostic methods (effluent analysis, cultures), and treatment (liposomal amphotericin B, catheter removal) were documented.
  • Antifungal susceptibility testing was performed.

Main Results:

  • The patient presented with asymptomatic black spots in her PD catheter lumen, leading to the diagnosis of peritonitis.
  • Initial cultures showed nonspecific mold, but final identification confirmed Ulocladium spp.
  • The isolate was sensitive to amphotericin B, and the patient responded well to treatment, successfully resuming PD.

Conclusions:

  • This case underscores the necessity of suspecting fungal PD peritonitis in relevant patients.
  • Prompt initiation of systemic antifungals and PD catheter removal are crucial for favorable outcomes in fungal PD peritonitis.
Keywords:
Peritoneal dialysisUlocladium speciescatheter-related infectionfungal peritonitisliposomal amphotericin B

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