Delta-Like Ligand 3 Expression Across Lung Neuroendocrine Subtypes: Interpreting Response in Small Cell Lung Cancer

Yitian Chen1, Li Liu1, Yang Ming1

  • 1Yitian Chen, PhD, Pharmaceutical Science, Faculty of Health Sciences, University of Macau, Macau SAR, China; Li Liu, MD, Department of Anesthesiology, Affiliated Hospital of Southwest Medical University, Sichuan, China, Department of Anesthesiology, The Fourth Affiliated Hospital of Southwest Medical University, Sichuan, China; Yang Ming, MM, Department of Neurosurgery, Affiliated Hospital of Southwest Medical University, Sichuan, China, Sichuan Provincial Clinical Disease Research Center for Neurosurgery, Sichuan, China; and Ligang Chen, MD, Department of Neurosurgery, Affiliated Hospital of Southwest Medical University, Sichuan, China, Sichuan Provincial Clinical Disease Research Center for Neurosurgery, Sichuan, China, Department of Neurosurgery, The Fourth Affiliated Hospital of Southwest Medical University, Sichuan, China.

Abstract

No abstract available in PubMed .

Related Concept Videos

Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.2K
Pleura of the Lungs01:13

Pleura of the Lungs

The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
6.8K
The Delta-to-Delta Circuit01:17

The Delta-to-Delta Circuit

In a delta-delta configuration, the source and the load are connected in a delta manner, forming a closed loop that divides the network into three distinct phases. This configuration makes the phase voltages identical to line voltages. Assuming the sources are in positive sequence, the phase voltages can be expressed directly without having a neutral wire.
1.1K
Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
4.5K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
5.5K
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
14.9K