Related Experiment Video
Updated: Jan 24, 2026
06:10
Encapsulated Cell Technology for the Delivery of Biologics to the Mouse Eye
Published on: March 30, 2020
8.3K
On-demand drug delivery with wireless technology.
Jannatul Ferdousi Emdadul Haque1, Arifur Rahman Nibir1, Md Annur Sadman1
1Department of Pharmaceutical Sciences, North South University, Dhaka 1229, Bangladesh.
Biomedical Materials (Bristol, England)
|January 22, 2026
Summary
Wireless on-demand drug delivery systems offer precise patient treatment by remotely controlling medication dosage and timing. Future integration of smart materials and closed-loop systems promises personalized medicine advancements.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- On-demand drug delivery systems (DDS) enable precise control over therapeutic agent release.
- Wireless DDS utilizes external stimuli (e.g., NIR light, magnetic fields) for remote drug release, overcoming wired limitations.
- Advances in nanomaterials and microdevices are crucial for developing sophisticated DDS.
Purpose of the Study:
- To review the advancements and clinical applications of wireless on-demand drug delivery systems.
- To highlight the potential of these systems in personalized medicine and chronic disease management.
- To discuss current challenges and future directions in the field.
Main Methods:
- Review of existing literature on wireless on-demand DDS.
- Analysis of enabling technologies such as nanomaterials, implantable microdevices, and wireless communication.
- Examination of clinical applications and case studies.
Main Results:
- Wireless on-demand DDS allows real-time dose adjustment, improving patient compliance and reducing hospital visits.
- Clinical applications include NIR-triggered cancer therapy, glucose-sensitive insulin delivery, and seizure-responsive neurotherapeutics.
- Integration of sensors, responsive polymers, and microelectronics enables targeted and personalized therapy.
Conclusions:
- Wireless on-demand DDS holds significant potential for enhancing therapeutic efficacy and minimizing side effects.
- Challenges remain in manufacturing, regulatory approval, and security.
- Future integration of smart materials, wireless power, and closed-loop systems will drive personalized medicine.
Related Concept Videos
01:16Drug Delivery: Overview
755
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
755
01:18Drug Delivery: Enteral Route
1.7K
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
1.7K
01:29Drug Delivery: Parenteral Route
1.6K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
1.6K
01:22Drug Delivery: Miscellaneous Routes
752
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
752
01:31Hybridoma Technology
17.3K
Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
17.3K
01:30Health Information Technology and Healthcare Information System
3.3K
Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
3.3K