Two-Year Follow-Up after Treatment with the Trenza Embolization Device for Wide-Neck Intracranial Aneurysms

Area of Science:

• Neuroendovascular therapy
• Cerebrovascular disease management
• Medical device innovation

Background:

• Broad-necked aneurysms pose treatment challenges due to their anatomy.
• The Trenza embolization device is designed for flow disruption to treat these aneurysms.
• Previous studies reported initial experiences with the Trenza device.

Purpose of the Study:

• To evaluate the 2-year outcomes of the Trenza embolization device for broad-necked aneurysms.
• To assess the durability and long-term safety of Trenza-assisted coiling.
• To report angiographic outcomes and late complications after treatment.

Main Methods:

• Observational, single-center, retrospective study of consecutive patients.
• Treatment of 6- to 12-mm broad-necked aneurysms (bifurcation or sidewall) with the Trenza device.
• Follow-up included 2-year angiographic assessment and monitoring for late complications.

Main Results:

• Twelve patients with 12 aneurysms (median diameter 9.6 mm) were treated.
• Adequate aneurysm occlusion (mRROC I-II) was achieved in 91% at 2 years.
• Complete occlusion (mRROC I) was achieved in 55%, with no late ischemic or hemorrhagic complications.

Conclusions:

• Trenza-assisted coiling demonstrates high and stable 2-year adequate occlusion rates for mid- to large-sized broad-necked aneurysms.
• The device is safe, with no late ischemic or hemorrhagic events observed.
• Trenza offers a durable treatment option for complex aneurysm configurations.